Plant genome editing through CRISPR-Cas holds transformative potential, yet its precision remains hampered by low gene targeting (GT) efficiency. This study presents a strategy to enhance CRISPR-based ...

Scientists at INRS have identified a family of enzymes, known as Ssn, that can make targeted cuts in single-stranded DNA—a feat never before achieved. This discovery not only fills a major gap in ...

“These exciting new data from coAAV-CSF-01 represent a major step forward in CNS gene therapy,” said Lolita Petit, CSO of Coave Therapeutics. “In non-human primates, the vector achieved robust brain ...

A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. The researchers designed STRAIGHT-IN with human ...