The DNA in our cells is constantly damaged, with the most severe being the simultaneous breakage of both strands that compose it. In a study published in Nature Communications, scientists reveal in ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

The evolutionary drive to maintain neurons that we see in jellyfish and sea anemones is perhaps one of the reasons why sleep is essential for humans today, Appelbaum said.

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...

QUICK FIX: From left, Frederick Alt and Guillermo Taccioli and their colleagues identified DNA-dependent kinase as a key enzyme involved in DNA repair. The way that DNA repairs itself recently has ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Francesca Storici, Georgia Institute of Technology (THE CONVERSATION) Your DNA is ...